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Description
While daily use is possible, most protocols recommend 3-5 times weekly to reduce potential tolerance development

And many people do

doi: 10.1016/j.nfs.2021.10.001
A.HsiehA.Al-FouadiM.CharbitA
A range of compounds emitted by CAFs, such as vascular endothelial growth factor A (VEGF-A), is noted to play a role in the stimulation and sustenance of T regulatory (Treg) cells, either directly or indirectly [46]

Rafehi, H., El-Osta, A
