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Kansanen E, Kuosmanen SM, Leinonen H, Levonen A-L

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Researchers are investigating its potential involvement in cell signaling, tissue repair, and metabolic pathways , among other applications

Consequently, adrenal hormone-related diseases like adrenal insufficiency and Cushings syndrome often show signs of oxidative stress, like fatigue, immune dysfunction, cognitive impairment, and accelerated aging (9)

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KEAP1, as an E3 ligase, negatively regulates NRF2 level