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In addition, hypoxia represents an inhibitory signal for GSH synthesis, since it decreases the activity of the two key biosynthetic enzymes GCL and GS [13]

Some of protective substances have the ability to reduce BaP metabolism, and in particular reduce the induction of cytochrome (CYP P450), which reduces the formation of oxidative metabolites, and therefore decreases ROS production

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[DOI] [PubMed] [Google Scholar] 92.Reiter R.J

Medications: Low-dose ACE inhibitor for BP, statin for vascular support

H., Alatawi, A., & Ali, S
