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One way that this reduction might occur is through desensitization, disassociation, or cointernalization of the dimer

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With appropriate oral B12 dosage, many individuals can successfully restore and maintain healthy levels without injections

doi: 10.3389/fcell.2025.1559300 Received 12 January 2025 Accepted 29 May 2025 Published 09 June 2025 Volume 13 - 2025 Edited by Ariane Zamoner, Federal University of Santa Catarina, Brazil Reviewed by Belm Sampaio-Marques, University of Minho, Portugal Heidar Heidari Khoei, Austrian Academy of Sciences (OeAW), Austria Updates Copyright 2025 Khodaei, Noori, Zare and Meshkin