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Our data obtained by knocking down GPx1, both in the human HEK293T cells and in rat neurons, together with the in vitro experiments, strongly suggest that endogenous -glutamylcysteine is a GPx1 cofactor for H 2 O 2 detoxification

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doi: 10.1002/jcb.21184 123 DarweishMMAbbasAEbrahimMAAl-GayyarMM

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