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Mechanisms Contributing to the Nephrotoxicity of Haloalkene Cysteine S -Conjugates: Toxicant Channeling Haloalkene cysteine S -conjugates are especially toxic to renal mitochondria (e.g., Anders et al., 1988, Chen et al., 2001, Groves et al., 1993, Lash and Anders, 1986)

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2013;120(8):160411 e4

In comparison, the pancreatic islets isolated from the GLP-1R knock-out mice secreted 2 to 4-fold less insulin after incubation with GLP-1 WT, GLP-1 QMP, or Exendin-4, similar amounts to that measured for unfused WT albumin (Fig

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