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however, it should be noted that CK can also be elevated, particularly mildly elevated, in neurogenic processes and situations in which cramps are common (see also HyperCKemia in this issue)

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Mitochondrial function assays, autophagy analysis, and extracellular signal-regulated kinase (ERK) signaling evaluations were conducted, including interventions with an ERK activator and autophagy inhibitor to probe pathway involvement