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Recent research shows that supplementing with the pyridoxine form of B6 at higher doses can paradoxically inhibit the creation of P5P.[ref] Researchers think that excess pyridoxine from high-dose supplements leads to the inhibition of PDXK, the enzyme that converts pyridoxine to P5P

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A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

The results showed that RIC significantly inhibited the inflammatory response, particularly in the classical and lectin pathways, as well as the upregulation of complement precursor levels