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325,326,327 The expression of Notch receptors is also upregulated during injury repair
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There are two major forms of AMD: (i) dry AMD, which accounts for 90% of diagnosed AMD cases and is characterized by the formation of drusen between Bruchs membrane and the retinal pigment epithelium (RPE), as well as the RPE and photoreceptor degeneration [214], and (ii) wet AMD, which is characterized by choroidal neovascularization (CNV) and involves the formation of new and leaky blood vessels driven by VEGF secretion, leading to macular edema, hemorrhage, and fibrous tissue proliferation [215,216]
10.1093/humrep/10.suppl_1.15 58 de Queiroz MelloA
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