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The art of oncology: when the tumor is not the targetnot just tired

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Role of carnitine in non-alcoholic fatty liver disease and other related diseases: An update

Desaturation and elongation of essential fatty acids The figure shows two vertical pathways of the metabolism of essential fatty acids, illustrating conversion to long-chain polyunsaturated fatty acids through desaturation (addition of a double bond) and elongation (addition of two carbon atoms) reactions: Omega-6 fatty acid pathway: At the top, linoleic acid (18:2n-6) is stepwise converted to 18:3n-6, then to 20:3n-6, then to 20:4n-6 (arachidonic acid), followed by conversion to 22:4n-6, 24:4n-6, 24:5n-6, and finally 22:5n-6

Intestinal absorption of carnitine reaches saturation level following administration of 2 g of carnitine, and the concentration reaches to its maximum level at 3.5 hr and then gradually decreases [20]