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Furthermore, although the two domains of the Fv fragment, V L and V H , can be coded for by separate genes, they can be joined, using recombinant methods, by a synthetic linker that enables them to be made as a single protein chain in which the V L and V- regions pair to form monovalent molecules (known as single chain Fv (scFv)
Limited proteolysis of high molecular weight histidine-rich protein of rat epidermis by epidermal proteinases

Frequently Asked Questions Glossary References Pickart L, Margolina A
doi: 10.3390/molecules21111449 106

If severe anemia is left untreated it can lead to heart failure
Carbon 81 , 158166 (2015)