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These enzymes were, therefore, not used for further screening experiments with the novel synthesised compounds
Elevated homocysteine levels can lead to the build-up of a molecule called S-Adenosyl Homocysteine (SAH)

doi: 10.1016/s0306-3623(97)00418-7

Free Radic Res 31:525534 Upadhyaya CP, Venkatesh J, Gururani MA, Asnin L, Sharma K, Ajappala H, Park SW (2011) Transgenic potato overproducing L-ascorbic acid resisted an increase in methylglyoxal under salinity stress via maintaining higher reduced glutathione level and glyoxalase enzyme activity

Administration of either agent to healthy mice produced features of reductive stress, underscoring the need to tailor dosing to baseline redox status
