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Atherosclerosis 2015;240:297304

Key functions of glutathione include: Detoxification : Glutathione helps the liver eliminate toxins and harmful compounds

Therefore, they constitute a platform for a complex set of interactions involving drug metabolism, protein haptenation, modulation of the inflammatory response, and/or generation of danger signals with implications in drug hypersensitivity reactions

Santarelli, L

Mahad, D., Ziabreva, I., Lassmann, H

To exclude potential off-target effects, two distinct lentiviral shRNAs targeting SLC25A39 (SLC25A39-sh1 and SLC25A39-sh2) were used to silence SLC25A39 expression in A549 and H1299 cells