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Drug-induced constipation: Opioid-induced constipation (OIC) is estimated to affect 4060% of patients on chronic opioid therapy

Schwannomas from one patient share the same constitutional mutations but have distinct somatic mutations

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We first measured metabolite abundance in cells that were depleted of KG by glutamine starvation or treatment with the IDH1 inhibitor (Fig

PMID: 182 JiangCXieSYangGWangN

While its hypophagic effect is well-attributed to GLP-1 receptor activation [15], the mechanisms through which its triple-receptor activity orchestrates the remodeling of adipose tissue itself, beyond caloric restriction, are poorly understood and likely key to its superior metabolic benefits