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Description
E3 is produced primarily from 16-hydroxy-dehydroepiandrosterone (DHEA) sulfate, 17-estradiol or E2 is formed from aromatization of testosterone, whereas E1 is derived from aromatization of androstenedione (Yaghjyan and Colditz, 2011)

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This can increase the risk of dose-dependent side effects , such as: Nausea Diarrhea Headache Fatigue Dizziness Insomnia Additionally, there is always a small, but serious risk, of serotonin syndrome when dealing with drugs that affect the neurotransmitter serotonin, as Lexapro does

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doi: 10.1186/1297-9716-43-35

Regulation of PD-L1 expression on cancer cells with ROS-modulating drugs
