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An earlier meta-analysis of small randomized, placebo-controlled trials had reported a positive impact of citicoline (1,000 mg/day, administered for 28 days to 12 months) on memory and behavior in subjects with cognitive deficits associated with cerebrovascular disorders (95)

None of the patients received either drug in the last one week prior to EEG, if at all

A specific role for eNOS-derived reactive oxygen species in atherosclerosis progression

To directly investigate the effects of vitamin E supplementation on insulin sensitivity in hypertension, in relation to the effects on circulating levels of reduced (GSH) and oxidized (GSSG) glutathione and on Mg [i] , we performed a 4-week, double-blind, randomized study of vitamin E administration (600 mg/d) versus placebo in 24 hypertensive patients and measured whole-body glucose disposal (WBGD) by euglycemic glucose clamp, GSH/GSSG ratios, and Mg [i] before and after intervention

Unlike the direct ionic mechanisms of metal-doped LDHs, the Se released from our nanocomposite serves a dual therapeutic function

However, treatment with sitagliptin only succeeded to normalize the relative liver weight (Figure 4)