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More importantly, epigenetic modifications are essential regulatory mechanisms for biological processes in the body, and recent studies have shown that ferroptosis is regulated by various epigenetic modifications, including DNA methylation, the RNA m 6 A modification and protein methylation[3, 8, 98, 99]

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There are eight GPX family members who have distinct cellular locations and substrate specificities, contributing to various physiological functions beyond their antioxidant roles [20]

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Accurate mass (3 ppm) and retention time (0.2 min) values were used for molecular assignment

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