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Description
Inadequate delta sleep is associated with impaired recovery, immune dysfunction, metabolic disturbances, and cognitive deficits

Sirtuins, another name for class III HDACs, are structurally distinct from the other classes and require a cofactor (NAD + ) for its activity (Mottet and Castronovo, 2008)
Common type 2 diabetes risk variant in MTNR1B worsens the deleterious effect of melatonin on glucose tolerance in humans

Bryan was my PT
This may explain why susceptibility to de novo leukemia has been so difficult to explain in persons without any obvious exposures to leukemogenic agents, such as benzene and ionizing radiation

121 Eriksson U, Titaley IA, Engwall M, Larsson M
