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showed that ROS generated by dysfunctional electron transport in mitochondria activate the inflammatory ASK1-P-p38 MAPK pathway [122]

System-Level Changes Clinical pathway redesign can reduce diagnostic delays by eliminating unnecessary steps and improving care coordination

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Langfelder and Horvath 2008) and Bayesian networks (Heckerman 1998) are commonly used, enabling the identification of regulatory modules and resilience mechanisms by linking genes, metabolites, and ions with traits