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These pathways were selected because they correspond to the core biological foundations of neurodegenerationproteinopathy, synaptic disfunction, neuroinflammation, mitochondrial impairment, vascular and metabolic dysregulation, among othersthereby anchoring the workflow in mechanisms that are central to dementias and making it applicable across AD, FTD, DLB, vascular and mixed dementias, as well as related neurodegenerative phenotypes that share these pathogenic mechanisms

Interactions between cancer cells and bone microenvironment promote bone metastasis in prostate cancer

K., Villacorte, D

doi: 10.1155/2019/8278454 108 YuL.LiQ.YuB.YangY.JinZ.DuanW.et al

This resistance is primarily driven by persistent expression of AR splice variants (e.g., AR-V7) and the HSP90-mediated stabilization of oncoproteins that sustain tumor survival and progression

In a racemic mixture, where R-ALA and S-ALA are equal, R-ALA reduction in mitochondria-rich tissues is generally unaffected
