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Cutting-edge directions and future prospects of astrocytic metabolism research In conclusion, while astrocytes have long been recognized for their supportive roles in the brain, current research is increasingly highlighting their active participation in brain energy metabolism and their potential involvement in neurological disorders

Contrasting Preclinical Promise with Human Data The central challenge for clinicians is the stark contrast between the vast, overwhelmingly positive body of preclinical BPC-157 evidence and the near-total absence of published, peer-reviewed human clinical trials

Restoring physiological levels of B vitamins through dietary supplementation or targeted interventions may offer new strategies to improve neuronal energy metabolism imbalance

Processed datasets generated during this study have been deposited in [Cho-Rok Jung] under accession number [BioProject: PRJNA1392668] to facilitate independent validation and secondary analyses

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