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Indeed, this is a difficult question to answer
doi: 10.1074/jbc.M113.529966
Merlos Rodrigo MA, Krejcova L, Kudr J, Cernei N, Kopel P, Richtera L, et al
High-dose supplementation, particularly hydroxocobalamin injections, has been associated with acne-like eruptions and rosacea flare-ups in susceptible individuals
Administration of exogenous ACTH normally stimulates the adrenal glands to produce cortisol, which can be measured to differentiate primary from secondary adrenal insufficiency
BPC-157 has not completed that process and is not FDA-approved for any human indication
