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Multiple diverse ligands binding at a single protein site: A matter of pre-existing populations

doi: 10.3389/fnmol.2026.1786336 Received 12 January 2026 Revised 21 March 2026 Accepted 07 April 2026 Published 21 April 2026 Volume 19 - 2026 Edited by Hiroyuki Aizawa, Aizawa Science Museum, Japan Reviewed by Sadaharu Miyazono, Asahikawa Medical University, Japan Arjan Kortholt, University of Groningen, Netherlands Alejandro Sandoval, Universidad Nacional Autnoma de Mxico, Mexico Updates Copyright 2026 Islam, Cppola-Segovia, Musso and Moore

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(2017) revealed that a plasma membrane-localized member of the nodulin 26-like intrinsic protein (NIP) plays a critical role in Al uptake and internal tolerance mechanism in Arabidopsis