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I became lethargic and could not focus: and had to leave work half a day

It is also advised to avoid mega doses of pyridoxine in pregnant or breastfeeding patients unless necessary, since safety data for doses beyond the recommended dietary allowance are limited

However, if you are sensitive to methylated nutrients or already reacting to supplements, starting with single-ingredient B12 may be safer before introducing a full B-complex

[1] A common starting regimen in adults with normal renal and hepatic function is 1 mL intramuscularly once or twice weekly, titrated every four weeks according to biochemical markers such as fasting lipid panel, liver transaminases, and serum carnitine

J Neurol Sci 316:18 [DOI] [PubMed] [Google Scholar] Luthra NS, Marcus AH, Hills NK, Christine CW (2020) Vitamin B12 measurements across neurodegenerative disorders