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This leads to TCII deficiency , making it hard for cells to get vitamin B12

Lupus may also cause narrowing of the blood vessels

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Early changes may include subtle improvements in body composition and slight reductions in waist circumference before significant weight loss occurs

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The injection delivers B12 directly into the bloodstream, making it the most reliable method for patients with absorption problems, pernicious anaemia, or gastrointestinal conditions affecting B12 uptake (such as Crohn's disease, coeliac disease, or following gastric surgery)