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FEBS J (2016) 283:37894

The desired biological response dictates the concentration and frequency

LFS: Formal analysis (supporting), Supervision (equal), Writing-reviewing and editing (equal), Funding acquisition (equal), Resources (equal)

Observation periods included the in-trial period (that is, while in the trial, regardless of treatment discontinuation or rescue intervention) and the on-treatment period (with trial product)

This is important because when we're talking about peptide therapeutics

The astragalus alkaloid and its derivatives are an important target for biological research because they are commonly found in food sources such as coffee, tea, and potatoes (Monteiro et al., 2016)