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While HR operates in the G2/S phase, when replication provides sister chromatids for the repair process, NHEJ is active throughout the cell cycle, particularly in G1
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Tachiiri H, Okuda Y, Yamasaki T, Kusakabe T

This suggests that cysteine deprived mitochondria can scavenge the significant ROS generated as a byproduct of persistent mitochondrial metabolism 32
