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developed glycosylated triple-interaction stabilized polymeric siRNA NPs (Gal-NP@siRNA) to target -site amyloid precursor protein cleaving enzyme 1 (BACE1) in an amyloid precursor protein (APP)/PS1 transgenic AD mouse model [68]

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Metabolomics analyses revealed a time-dependent increase in tricarboxylic acid cycle intermediates during ES treatment, suggesting that copper toxicity primarily disrupts the tricarboxylic acid cycle rather than oxidative phosphorylation (180,181)

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Comparison of the radical trapping ability of PBN, S-PPBN and NXY-059

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