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By removing m 6 A marks from CHAC1 mRNA, ALKBH5 decreases its stability, leading to reduced CHAC1 expression

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More recently, miR-141-3p, downregulated by lncRNA HIF1A-AS2, has been shown to promote CRC metabolic reprogramming and proliferation through FOXC1 activation, highlighting additional post-transcriptional networks under hypoxic stress [114]

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