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Indeed, by activating toll-like receptor 2 (TLR2), it promotes keratinocyte proliferation via interleukin-1 alpha (IL-1), resulting in comedogenesis (i.e
Mukha D, Dessain J, OConnor S, Pniewski K, Bertolazzi F, Patel J, et al
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APOE4 increases risk, accounting for ~65% of AD cases (Mayeux et al., 1998)
Bosshart PD, Kalbermatter D, Bonetti S, Fotiadis D
