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But IGF1 LR3 is not without risks

Teach patients about the importance of strength and dose

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Answer: Good candidates are adults struggling with persistent hunger, a stalled response to GLP-1 medications, insulin resistance, or a long history of weight cycling, who want to address the hormonal driver of appetite rather than rely on restriction alone

What exists is preclinical, and it is thin: Rodent and in-vitro work described procognitive and synaptogenic effects (McCoy 2013, PMID 23055539 now under an Expression of Concern

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