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A procedure called Kasai hepatoportoenterostomy (KPE) that replaces the obliterated extrahepatic bile duct with an intestinal conduit is the first-line treatment to re-establish the bile flow with only 50% success rate ( BA is most likely a clinical phenotype resulting from a number of prenatal or perinatal insults to the hepatobiliary tree, and this disease is underpinned by a number of key pathobiological factors (KPFs) either singly or more often in combinations

The cell detection tool was used on the DAPI channel to make sure that only a cell was recognised and not the background or artefact by system

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Peptide dosing, timing, and combination protocols require medical expertise

(Mie, Japan)

These insights offer potential targets and a theoretical framework for future developments