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Some mutations accelerate intestinal tumor formation, 210 while MT-CYTB and MT-CO1 variants enhance tumor growth through ROS-induced NF-B2 activation
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doi: 10.1016/S0002-9343(98)00070-9
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On the other hand, Nrf2-deficient mice have been shown to be susceptible to cigarette smoke-induced emphysema [265], hyperoxic lung injury [266], and pulmonary fibrosis [267]
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