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Evidence for vitamin E/K and minerals such as iron, calcium, and magnesium remains weak or very low, with insufficient human data

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Although most studies investigating the OLG life cycle have been conducted in animal models, there is significant evidence to suggest that DNA methyltransferases and DNA methylation are dynamic in the processes of OPC specification, survival, proliferation, differentiation, and myelination [68, 70, 83, 104, 105]