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The TfR remains the most extensively studied target due to its abundant expression at the BBB and its well-characterized transcytosis pathway, and it has been widely leveraged to enhance CNS delivery of antibodies and enzyme inhibitors relevant to AD (Shen et al., 2025)

KirkPSheppardMCarpenterJPAndersonLHeTSt PierreTet alPost-mortem study of the association between cardiac iron and fibrosis in transfusion dependent anaemia

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