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Targeting the key enzymes and molecules involved in the ferroptosis process is one potential approach to developing ferroptosis inhibitors for cancer treatment

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Our results demonstrated that GYY4137 is endowed with anti-inflammatory effects and serves as a key regulator of redox signaling to alleviate mitochondrial oxidative stress and protect synovial macrophages from pyroptosis

Exercise Mimetic and Cellular Adaptation Effects MOTS-c levels increase following physical activity, indicating responsiveness to metabolic demand

The results of the above-mentioned analyses demonstrated that with the increase in the degree of ferroptosis, the overall resistance of HK-2 cells to oxidation weakened, and the degree of lipid peroxidation increased in the high-concentration CaOx envi-ronment