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In contrast, whereas about 45% of the patients in the placebo arm showed some improvement, only ~12% showed a 50% improvement

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By contrast, the broadly neutralizing antibody (bnAb) 2G12 (Box 2) was shown to reversibly neutralize HIV post-attachment, probably by interfering with virusCCR5 interaction 26

A separate analysis in Nature Medicine found that retatrutide produced significant reductions in liver fat content in participants with metabolic dysfunction-associated steatotic liver disease (MASLD), suggesting benefits beyond simple weight reduction

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