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Increasingly, systemic metabolic disorders such as diabetes mellitus have been linked with increased bone fragility in human patients

The MAPK phosphatases have a similar catalytic site (VHCX5R(S/T)) (74, 75), with cysteine being essential for MAPK dephosphorylation

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Zimmerman MT, Bayse CA, Ramoutar RR, Brumaghim JL
