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As cells age, mitochondria can become less efficient, leading to a decline in overall cellular function

The antiplatelet ticlopidine [138] is affected in extended Phase I metabolism, which is correlated with its bioactivation, giving rise to multiple GSH S-adducts

Duce, J

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Haas et al., 2008), which store histamine in granules, which are released when appropriately activated (Forsythe, 2019)
