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14 , Suppl 1) with roles in lipid metabolism 15 and linked to ASD

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2004;287:R1244R1249

Sekhar RV, Patel SG, Guthikonda AP, Reid M, Balasubramanyam A, Taffet GE, Jahoor F

There are currently two anti-PCSK9 antibodies: alirocumab (trade name Praluent) and evolocumab (trade name Repatha) that are approved for use in hypercholesterolemia A third anti-PCSK9 monoclonal antibody, bococizumab, was in the process of development but was discontinued after reports of drawbacks including the formation of anti-drug antibodies, injection-site reactions, and significant variability in cholesterol-lowering effects (Ridker et al., 2017)

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