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[95] [19] [96] The amount of cyanide in cyanocobalamin is generally not considered a health risk, since even in a 1,000 g dose, the 20 g of cyanide it contains is less than the daily consumption of cyanide from food

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Most of the increase in cobalamin concentrations was achieved by the end of the first week of treatment (Figure 1)

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With cyanocobalamin or methylcobalamin, rare skin reactions (acne/rosacea) and gastrointestinal disturbances may occur