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DIO2 is largely responsible for the local conversion of T4 to T3 in extrathyroidal target tissues ( Reference Kohrle, Jakob and Contempre 69 )
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This compound has anti-inflammatory, antibacterial and antioxidant properties and specifically improves wound healing [18]
The level of estradiol and progesterone, which are associated with the pathogenesis of UF, was also lowered with high-dose LD (Wang et al., 2020)
Lancet 2:7786, 1972
