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Goulas, A., Betzel, R

Accordingly, loss of SIRT4 enhances glutamine-dependent proliferation and genomic instability, which simultaneously contribute to tumorigenesis 151

PD-MCI in the posterior cingulate cortex exhibited reduced N-acetyl aspartate (NAA), total NAA, choline, glutathione, glutamate + glutamine, and total creatine (tCr) levels but both elevated myo-inositol (Ins) and Ins/tCr ratio, but reduced NAA/Ins ratio

In fungi the metabolic gene clusters are often associated with fungal virulence, and evolutionarily with pathways conferring some advantage over competitors

& Haas, H

An EF of 40% or less confirms HFrEF