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Description
TGF--dependent signaling, activated by soluble endoglin and growth differentiation factor 15, promotes inflammatory chemokines in the ovary and pelvic adhesions, contributing to reduced fertility (44)

Moreover, the ability of polyphenols to penetrate the BBB is compound specific and often suboptimal, necessitating advanced delivery strategies such as nanoformulations or prodrugs to enhance CNS targeting (Ramakrishna et al

The first pharmacometabolomics studies on acetaminophen aimed to identify the biomarkers of drug-induced liver injury (DILI) [86,87]

doi: 10.2460/ajvr.2004.65.1100

Its return to normal in liver disease is an excellent indicator

HFrEF, heart failure with reduced ejection fraction
