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After stopping the offending drug without improvement of renal function over 4 weeks, the patient received eculizumab resulting in improvement and stabilization of kidney function

Specifically, experimental data suggest it interacts with VEGFR2 via Src-caveolin-1-eNOS and PI3K-Akt-eNOS axes

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Injections are more frequent because of improved absorption and bioavailability

Both produce significant weight loss, but tirzepatide has shown greater average weight loss in clinical trials (approximately 22.5% vs 14.9% at comparable timepoints)

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