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[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Yuen R.K., Avila L., Peaherrera M.S., von Dadelszen P., Lefebvre L., Kobor M.S., Robinson W.P

First, obesity-related GH resistance in the liver, such as that characteristic of fatty liver, reduces IGF-1 production, leading to decreased serum IGF-1 levels 15