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This epigenetic silencing effectively inhibits class-switch DNA recombination (CSR), somatic hypermutation (SHM), and plasma cell differentiation, thereby reducing the production of both T-dependent and T-independent autoantibodies (e.g., anti-dsDNA antibodies)

There has also been improvement in patient and surgeon education regarding the potential benefits of CPNBs

The concept of utilizing VitC as a therapeutic agent for cancer care was first introduced by double Nobel Prize winning chemist Linus Pauling and physician Ewan Cameron almost 50 years ago [68]

doi: 10.1021/jasms.4c00125 5 RanjanSGautamA

The actual duration of the results is unknown as with different people the results vary

J Clin Oncol 2021 ASCO Annual Meeting 39(suppl