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, Yeatman T
It is a cytotoxic -oxoaldehyde compound that is highly reactive and produced through different enzymatic and non-enzymatic reactions
(3) found that PE can be oxidized by acyl-CoA synthetase long chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3) and further oxidized to lipid peroxides by lipoxygenase-15 (LOX-15)
This result was confirmed in a rat middle cerebral artery model [63, 64] as well as in stroke patients [65]
doi: 10.1016/S1470-2045(08)70038-X
Kojic acid also neutralises oxidative stress, preventing pigmentation from worsening
