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Abstract Parkinsons disease (PD) is the second neurodegenerative disorder most prevalent in the world, characterized by the loss of dopaminergic neurons in the Substantia Nigra (SN)

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In 1977, an in vivo experimental study with rats showed that the cerebral activity of glutathione peroxidase, a selenoprotein responsible for peroxide detoxification, was significantly decreased after MeHg exposure (Prohaska and Ganther, 1977)

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