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Physiol Rev (2007) 87(1):245313

Tight-binding inhibitors efficiently inactivate both reaction centers of monomeric Plasmodium falciparum glyoxalase 1
Xin L, Che B, Zhai B, Luo Q, Zhang C, Wang J, et al
doi: 10.1002/14651858.CD001447.pub3 26

NAC & analgesic effect: a mechanistic overview As a precursor to the critical antioxidant glutathione [11] and with profound antioxidant properties, NAC may have therapeutic potential in various medical conditions associated with oxidative stress and inflammation

Unhealthy brains consistently have lower glutathione and higher markers of oxidative stress
